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5-HT Receptor


5-HT receptors (5-hydroxytryptamine receptors,The serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand.

  • Fluoxetine HCl EY0380

    Fluoxetine hydrochloride是选择性5羟色胺再吸收抑制剂（SSRI）。

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  • Agomelatine EY0374

    Agomelatine是人和猪的5-HT2C受体竞争性拮抗剂，pKi分别为6.2和6.4。

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  • Mirtazapine EY0330

    Mirtazapine是抗抑郁的5-HT受体抑制剂。

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  • Venlafaxine EY0307

    Venlafaxine hydrochloride 是5-羟色胺和去甲肾上腺素重吸收抑制剂（SNRI）。

    More

  • Eletriptan HBr EY0304

    Eletriptan HBr 是一种选择性的5-羟色胺1B和1D受体激动剂，Ki值分别为0.92 nM和3.14 nM。

    More

  • Fluoxetine HCl EY0380

    Fluoxetine hydrochloride是选择性5羟色胺再吸收抑制剂（SSRI）。

    More

  • Agomelatine EY0374

    Agomelatine是人和猪的5-HT2C受体竞争性拮抗剂，pKi分别为6.2和6.4。

    More

  • Mirtazapine EY0330

    Mirtazapine是抗抑郁的5-HT受体抑制剂。

    More

  • Venlafaxine EY0307

    Venlafaxine hydrochloride 是5-羟色胺和去甲肾上腺素重吸收抑制剂（SNRI）。

    More

  • Eletriptan HBr EY0304

    Eletriptan HBr 是一种选择性的5-羟色胺1B和1D受体激动剂，Ki值分别为0.92 nM和3.14 nM。

    More
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